The Lady Bears started on a 17-1 run that ended with a 96-46 victory over Grambling State.
Tigers leading scorer Shakyla Hill was not allowed a field goal until the fourth quarter.
Baylor, on the other hand, enjoyed a hot start from junior Lauren Cox. The forward had a double-double after the first quarter and finished with a career-high 30 points and added 17 rebounds.
Running mate Kalani Brown notched yet another double-double and senior Dekeiya Cohen also reached double-figure scoring.
Baylor advances to the second round where they will play Michigan on Sunday, March 18.
Tip-off has not yet been announced.
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